motor neurons in Drosophila
Motor neurons in Drosophila (Carrillo Lab)

Research

The Department currently represents research on a wide range of biological problems and systems – its internationally recognized strengths include:

  • invertebrate and vertebrate development
  • plant development and plant pathogen interactions
  • molecular biology
  • microbiology
  • cellular structure and function

 

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Faculty Research Topics

How do living cells organize and coordinate their many activities in space and time?  CMB faculty address this question through studies of cell and tissue polarity, membrane trafficking, self-organized cytoskeletal dynamics that underlie cell motility, shape change and cell division, cell cycle control and circadian dynamics.

Robert Carrillo

Richard Fehon

Benjamin Glick

Michael Glotzer

Jean Greenberg

Sally Horne-Badovinac

David Kovar

Stephen Kron

Heng-Chi Lee

Jocelyn Malamy

Edwin Munro

David Pincus

Micheal Rust

Aaron Turkewitz

Sampriti Mukherjee

 

 

Much of organismal development is governed by the actions of individual cells that must be coordinated to produce coherent tissue-level behaviors. CMB researchers study the collective dynamics of cells that underlie spatiotemporal control of cell identity, growth control, tissue morphogenesis, the elaboration of neural circuits, and the neural control of animal behavior.

Richard Fehon

Edwin Ferguson

Michael Glotzer

Sally Horne-Badovinac

Jocelyn Malamy

Edwin Munro

Ilaria Rebay

An enduring challenge in cell biology is to understand how cells control the flow of genetic information, within and across generations, through dynamic regulation of genome organization, the synthesis, modification, repair and destruction of nucleic acids. CMB researchers address this challenge through studies of transcriptional control, RNA splicing, meiotic recombination and DNA repair, regulation of chromatin architecture and dynamics, and genome surveillance.

Douglas Bishop

Stephen Kron

Heng-Chi Lee

Laurens Mets

David Pincus

Ilaria Rebay

Lucia Rothman-Denes

Alexander Ruthenburg

Jonathan Staley

Cells use elaborate biochemical circuits to integrate information and make informed decisions.  CMB researchers explore core principles of biological circuit design that underlie cell cycle control, cell fate determination, cellular metabolism, cell and tissue homeostasis, disease resistance, maintenance of genome integrity, and the neural control of behavior.

Robert Carrillo

Richard Fehon

Edwin Ferguson

Michael Glotzer

Jean Greenberg

Elizabeth Heckscher

Steve Kron

Edwin Munro

David Pincus

Illaria Rebay

Michael Rust

Sampriti Mukherjee

 

Research Resources